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عمومی::
تراوش فعال
Some of the known mechanisms of AMR include impermeability to drugs by
altering the microbial cell wall,elimination of drug through active efflux
, inactivation of the drug through enzymatic action
, alteration of the drug receptor site through mutation
, and through a catabolic
pathway that disintegrates the antibiotic .
Antibiotic resistance can spread by the horizontal transmission of specific genomic
resistance mechanisms and the selection/propagation of resistant strains, which
is known to occur asymptomatically between humans, animals, and the environment,
through what is named as the lateral antibiotic resistance genetic transfer
(LARGT) pathways.
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